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Milan, Italy

Niguarda Hospital
(Grande Ospedale Metropolitano Niguarda)

The Niguarda Hospital is one of the main clinics in Milan, Italy. It is a scientific and educational center that combines the treatment of complex pathologies and continuity of care.

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About the Niguarda Clinic

A large general hospital. Highly qualified specialists here provide medical care at the highest level, from diagnosis to rehabilitation, even in urgent and very complicated cases. Thus, by applying to this clinic, a foreign patient will receive the whole range of necessary services.

Since its opening on October 10, 1939, the clinic has steadily improved.
Especially in recent decades, it has undergone complex structural organizational changes that have made communication and efficiency of treatment only better.

Main features of the Nyguarda Clinic
Areas of treatment at the Niguarda Clinic
Niguarda Clinic Research Work
How to begin treatment at the Niguarda Clinic

Main features of the Nyguarda Clinic

The Niguarda Clinic offers patients advanced solutions and individualized treatment through the use of diagnostic technology and innovative methods. It is popular not only among Italian patients, but also among foreign nationals. The clinic does everything in its power to provide the highest level of medical care, has state-of-the-art technical equipment and highly qualified personnel.
Comprehensive assistance
The Nyguarda Clinic provides treatment with a multidisciplinary approach for all diseases of adults and children.
Treatment of very complex pathologies
The hospital treats very complex pathologies due to its highly qualified specialists, emergency care skills and multidisciplinary approach.
Continuity of care
Thanks to local services and facilities, as well as cooperation with outside organizations, Nyguarda provides both inpatient and outpatient care at a high level.
Scientific and Educational Center
Seeking to improve their knowledge and skills in the delivery of medical care, specialists are willing to learn, experiment and conduct research. Niguarda is a center of excellence in medical research for physicians who require highly accredited training.

Areas of treatment at the Niguarda Clinic

The Nyguarda Clinic is a broad-based medical facility and provides treatment for a variety of diseases in both adults and children. All medical disciplines and technologies are present, from diagnosis to rehabilitation. This ensures quality treatment in urgent and complex cases.
Orthopedics and Traumatology


The Department of Ophthalmology at the Niguarda Clinic performs surgical treatment of all major eye pathologies.
A special place is given to vitreoretinal surgery for the treatment of retinal detachment, diabetic retinopathy, and macular degeneration.
Eye diseases are diagnosed with fluoangiography and angiography with indocyanine green to study retinal diseases, for which OCT (optical coherence tomography) technology is also used, corneal topography.
Main pathologies and treatment methods
  • orbits (inflammatory orbitopathies, general diseases, neoplasms, injuries)
  • eyelids (ectropion, lagophthalmos, inflammatory blepharopathies, neoplasms, injuries)
  • lacrimal system (injuries, malformations)
  • conjunctivae
  • cornea (inflammatory, degenerative, traumatic, congenital)
  • sclera (inflammatory, degenerative, traumatic, congenital)
  • vasculature of the eye (inflammatory, degenerative, traumatic, congenital)
  • retina (vascular, inflammatory, associated with general, degenerative, tumor, trauma, congenital diseases, retinal detachment, macular tubercle)
  • lens (cataract)
  • vitreous body (inflammatory, degenerative)
  • hydrodynamics (glaucoma of all types, hypotension of all types)
  • optic nerve and visual pathways (vascular, inflammatory, toxic, degenerative, tumorous, traumatic)
  • musculoskeletal system (strabismus)
  • refractions (myopia, hyperopia, astigmatism, presbyopia, aphakia)
  • ocular pathology in relation to systemic diseases
  • corneal surgery (perforative keratoplasty, deep anterior lamellar keratoplasty-DALK, refractive keratoplasty, keratoprosthesis with implant)
  • anterior segment surgery (treatment of cataracts surgically to restore missing dioptres; glaucoma using advanced techniques such as viscocanalostomy, deep sclerectomy, and drainage canal implantation)
  • tear duct surgery
  • surgery of ocular and anophthalmic cavity, extraocular musculature
  • refractive surgery.

Dr. Marcelo Pisani

Head of the Department of Ophthalmology

Worked in adult ophthalmology at Niguarda.

Conducts advanced training courses.

Since 2016 he has been acting head of the department of ophthalmology.

Performed about 6,000 surgeries.

Orthopedics and Traumatology

The Niguarda Clinic Department is primarily dedicated to the care of polytrauma and fracture patients. The specialists also provide care for basic orthopedic pathologies, which can affect different parts of the body. This structure has developed special expertise in treating diseases in their early stages and is able to provide care even in cases where multidisciplinary emergency intervention is necessary.

Main pathologies and treatment methods
  • pelvic and acetabular surgery
  • shoulder, knee, and ankle ligament reconstruction
  • sports trauma surgery
  • first and revision orthopedic surgery
  • arthroscopic surgery and cartilage transplantation
  • traumatic and non-traumatic spine surgery
  • hand surgery and microsurgery
  • orthopedic surgeries in hemophiliacs, on dialysis, allergic to latex, or suffering from disabling, systemic and chronic conditions
  • foot surgery, pediatric orthopedics and functional orthopedic surgery for children with cerebral palsy

Dr. Dario Capitani

Head of the Department of Orthopedics and Traumatology

He worked at the J. Pini Center for Sports Traumatology as a research associate and then as an assistant in Orthopedics and Traumatology.

Orthopedic trauma specialist for professional and non-professional athletes in various sports disciplines (cycling, rugby, american soccer, basketball, etc.).


The entire spectrum of neurosurgical pathologies - from neuro-oncology to cerebral arteriovenous malformations - is treated in the Department of Neurosurgery at the Niguarda Clinic for patients of all age groups.

Minimally invasive procedures are applied and the most complex reconstructive techniques are used.
Brain and spinal cord tumors of any localization, origin and size are most commonly treated.
In the neurosurgery department, advanced innovative methods of treatment of vascular malformations and brain tumors are being developed.

Minimally invasive surgical techniques (e.g., targeted access techniques to the skull base, gamma knife radiosurgery, and endoscopic techniques performed in collaboration with otorhinolaryngology) have been developed.
Other procedures developed include anterior access interventions to the spine and neuroendoscopy for the treatment of hydrocephalus, intracranial cysts and ventricular tumors.

Main pathologies and treatment methods
  • skull base surgery
  • treatment of cerebral aneurysm
  • cerebral arteriovenous malformations and dural arteriovenous fistulas of the brain and spinal cord
  • complex pathologies (tumors, injuries, infections) of the spine
  • malformations (Arnold Chiari malformation)
  • spine (lipomas and myelomeningocele)
  • neuroendoscopic treatment of hydrocephalus and intracranial cysts
  • complex craniosynthesis, including rigid osteosynthesis

Dr. Marco Cenzato

Head of the Department of Neurosurgery

Since 2011, he has been the head of the Department of Neurosurgery at the Niguarda Clinic.

He has extensive experience in all areas of cranial and spinal neurosurgery, as well as in

Vascular neurosurgery, in particular the treatment of arteriovenous malformations (AVMs), cavernous angiomas of the brainstem, complex intracranial aneurysms and brain revascularization procedures (shunting).


The institution is designed for the prevention, diagnosis and treatment of kidney diseases.
The Niguarda Clinic's Nephrology Department also plans appropriate therapy for individual cases with ongoing monitoring. When renal function is finally impaired, it is the task of the nephrologist to determine and suggest the best alternatives, such as dialysis treatment (in hospital or at home) or a kidney transplant.

The institution participates in national and international clinical research protocols, in new approaches for the therapy of anemia and osteodystrophy associated with uremia, and in new immunosuppressive drugs in kidney transplantation. It is part of a multidisciplinary team that performs pancreatic islet transplants in patients with type 1 diabetes, experimenting with new engraftment sites.

Main pathologies and treatment methods
  • all forms of renal failure (primary and secondary to systemic diseases)
  • kidney stones
  • renal tubulopathies, including congenital
  • abnormalities of electrolytes and calcium metabolism
  • dialysis to artificially compensate for the loss of natural organ function
  • kidney transplantation for complete restoration of patients' quality of life.
Priority is given to kidney transplantation from a living donor (related or unrelated)
  • combined kidney and pancreas transplantation in diabetic patients with renal insufficiency
  • isolated transplantation of the pancreas or pancreatic islets to restore endocrine function in patients with type 1 diabetes
  • rare diseases: cystinuria, Gitelman syndrome and Bartter syndrome, nephrogenic non-sugar diabetes, spongy kidney, Alport syndrome, vasculitis with kidney damage, cryoglobulinemia, primary and familial amyloidosis.

Dr. Enrico Eugenio Minetti

Head of the Department of Nephrology

Membership in associations:

Italian Society of Nephrology (SIN)

European Association of Dialysis and Transplantology - European Renal

Association (EDTA - ERA)

European Society for Organ Transplantation (ESOT)

Italian Society of Organ Transplantology (ISOT)

American Society of Nephrology (ASN)


The Cardiology Department of the Niguarda Clinic provides hemodynamics, treatment of heart failure, electrophysiological studies, diagnosis and rehabilitation.

Hemodynamic Cardiology. It deals with the treatment of all acute coronary syndromes, in particular acute myocardial infarction. The most modern technologies of endocoronary thromboaspiration and new systems for circulatory support in cases of severe cardiac pump insufficiency are used.

Main pathologies and treatment methods

  • structural heart disease;
  • a referral center for therapy of complicated coronary heart disease;
  • percutaneous treatment of aortic stenosis and valve prosthesis dysfunction (both biological and mechanical) using minimally invasive surgery;
  • monitoring of patients who have undergone percutaneous implantation of an aortic prosthesis or patients with aortic or mitral valve heart disease;
  • thanks to joint work with other teams, specialists of the cardiology department treat persistent arterial hypertension with ablation of the renal sympathetic innervation.

Heart failure. Patients with heart failure, patients awaiting transplantation, transplant recipients and patients with mechanical circulatory assist systems ("artificial hearts") are monitored here.

The main pathologies and methods of treatment:

  • acute and chronic heart failure of any origin;
  • primary and secondary cardiomyopathies, myocarditis, rare heart disease;
  • carriers of mechanical circulatory support ("artificial heart");
  • heart transplantation.

Electrophysiology. The department deals with the diagnosis and therapy of cardiac arrhythmias and is characterized primarily by interventional electrostimulation and electrophysiology.

The main pathologies and methods of treatment:

  • clinical and interventional arrhythmology;
  • implants and replacement of conventional pacemakers;
  • implants and biventricular pacemaker replacements for cardiac resynchronization therapy;
  • non-lethal pacemaker implants;
  • implants and automatic defibrillator replacements;
  • external and internal electrical cardioversion.

Diagnosis and rehabilitation.  Activities are organized into hospitalization, diagnostic and rehabilitation areas . Cardiology hospitalization mainly deals with coronary heart disease and valve pathologies, but, in cooperation with other structures, it deals with all cardiological pathologies - from diagnosis to the interventional phase.

The main pathologies and methods of treatment:

  • coronary heart disease;
  • heart valve defect;
  • hypertensive and diabetic heart disease;
  • dilated cardiomyopathy;
  • heart failure;
  • congenital heart defects in adults;
  • arrhythmias.

Dr. Giuseppe Cattafi

Head of the Department of Electrophysiology

He has gained considerable experience and expertise in the implantation and replacement of single-, dual-chamber and atriobiventricular pacemakers (PM) and automatic defibrillators (ICD), loop recorder implants, radiofrequency transcatheter avulsions, atrial fibrillation cryoablation, electric cardioversion.

Extensive experience in implantation of cardiac resynchronization therapy (CRT) devices.


Specialists in the Oncology Department at the Niguarda Clinic conduct clinical research on the treatment of solid tumors.

The Department of Oncology collaborates with the Niguarda Center for Sterility in the cryopreservation of gametes to guarantee reproductive options for people whose cancer or treatment methods threaten their ability to have children.

The department also specializes in less common cancers, such as nasopharyngeal tumors and germinal neuroendocrine tumors.
The interdisciplinary treatment of solid tumors uses high-tech diagnostic methods, such as advanced radiological diagnostics and integrated nuclear diagnostics.

Dr. Salvatore Siena

Head of Oncology Department

He worked at the National Cancer Institute in Milan as researcher, assistant and deputy head of the Oncology Department and then at the IRCCS Istituto Clinico Humanitas in Milan as head of the Bone Marrow Transplantation and Oncology Treatment Development Department.

He is currently the head of the Falck Oncology Department, the Department of Hematology and Oncology and the Niguarda Sencer Center at the Niguarda Hospital in Milan. Professor of Medical Oncology at the University of Milan.

Niguarda Clinic Research Work

Niguarda is a public hospital specializing in the treatment of a wide range of diseases.
The clinic conducts extensive research into new therapies with the support of international collaborations.
In recent years, there has been a positive trend in clinical research in neurology, diabetology, pain therapy, gene therapy, cardiovascular diseases, hematology, and oncology, which has led to improvements in therapy in these areas.

The availability of professional skills, technological competencies, certified laboratories and high complexity patients make Nyguarda a unique and interesting partner to collaborate with. It offers specific opportunities for pharmaceutical and biotechnology companies looking for a reliable and experienced clinical/scientific partner.

A major advantage is the high volume of diagnostic/therapeutic interventions, which ensures optimal integration of research and patient care. This defines Nyguarda as one of the best clinical sites for translational research.

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